Sheldon Cooper vs. Wil Wheaton
This feud has been simmering for years—since Sheldon Cooper was 15 years old to be exact. Wheaton has stirred up some serious drama since then. He tricked Sheldon into losing the Mystic Warlords of Ka’a tournament, he broke up Leonard and Penny’s relationship to win a bowling competition, and he has thrown his celebrity status in Sheldon's face on more than a few occasions.
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