Average Annual Death Toll: 100
Lions, unlike most of the animals on this list, are known to actively hunt and eat humans. American and Tanzanian scientists have reported that at least 563 villages were attacked from 1990 to 2005.
The most notorious killer lions were the Tsavo Man-Eaters, two mane-less lions responsible for killing and eating up to 135 workers on the Kenya-Uganda Railway in a mere nine months in 1898. Rawr!