A Look Back: The Big Bang Theory Series Premiere

THE BIG BANG THEORY is a comedy about brilliant physicists Leonard (Johnny Galecki, not pictured) and Sheldon (Jim Parsons, not pictured), who are the kind of "beautiful minds" that understand how the universe works, but none of that genius helps them interact with people, especially women. All this begins to change when a free-spirited beauty named Penny (Kaley Cuoco, pictured left) moves in next door. Sheldon, Leonard's roommate, is quite content spending his nights playing Klingon Boggle with their socially dysfunctional friends, fellow Cal Tech scientists Wolowitz (Simon Helberg, pictured middle) and Koothrappali (Kunal Nayyar, pictured right). Photo: Robert Voets/CBS ©2007 CBS Broadcasting Inc. All Rights Reserved.

THE BIG BANG THEORY is a comedy about brilliant physicists Leonard (Johnny Galecki, not pictured) and Sheldon (Jim Parsons, not pictured), who are the kind of "beautiful minds" that understand how the universe works, but none of that genius helps them interact with people, especially women. All this begins to change when a free-spirited beauty named Penny (Kaley Cuoco, pictured left) moves in next door. Sheldon, Leonard's roommate, is quite content spending his nights playing Klingon Boggle with their socially dysfunctional friends, fellow Cal Tech scientists Wolowitz (Simon Helberg, pictured right) and Koothrappali (Kunal Nayyar, not pictured). Photo: Robert Voets/CBS ©2007 CBS Broadcasting Inc. All Rights Reserved.

THE BIG BANG THEORY is a comedy about brilliant physicists Leonard (Johnny Galecki, not pictured) and Sheldon (Jim Parsons, not pictured), who are the kind of "beautiful minds" that understand how the universe works, but none of that genius helps them interact with people, especially women. All this begins to change when a free-spirited beauty named Penny (Kaley Cuoco, pictured left) moves in next door. Sheldon, Leonard's roommate, is quite content spending his nights playing Klingon Boggle with their socially dysfunctional friends, fellow Cal Tech scientists Wolowitz (Simon Helberg, pictured right) and Koothrappali (Kunal Nayyar, not pictured). Photo: Greg Gayne/Warner Bros. ©2007 Warner Bros. Television. All Rights Reserved.

Brainy best friends Leonard (Johnny Galecki, right front) and Sheldon (Jim Parsons, right), who can tell you anything you want to know about quantum physics, but when it comes to dealing with everyday life here on earth, they're lost in the cosmos. Neither fully understands that scientific principles don't always apply in matters of the heart - until they meet their sexy new neighbor, Penny (Kaley Cuoco, left), a friendly screenwriter/waitress from the Midwest who also happens to be newly single, on the series premiere of The Big Bang Theory. Photo: Greg Gayne/Warner Bros. ©2007 Warner Bros. Television. All Rights Reserved.

THE BIG BANG THEORY is a comedy about brilliant physicists Leonard (Johnny Galecki, second from left) and Sheldon (Jim Parsons, second from right), who are the kind of "beautiful minds" that understand how the universe works, but none of that genius helps them interact with people, especially women. All this begins to change when a free-spirited beauty named Penny (Kaley Cuoco, pictured middle) moves in next door. Sheldon, Leonard's roommate, is quite content spending his nights playing Klingon Boggle with their socially dysfunctional friends, fellow Cal Tech scientists Wolowitz (Simon Helberg, pictured far left) and Koothrappali (Kunal Nayyar, pictured far right). However, Leonard sees in Penny a whole new universe of possibilities... including love. Photo: Monty Brinton/CBS ©2007 CBS Broadcasting Inc. All Rights Reserved. Flash t-shirt courtesy DC Comics

When Leonard (Johnny Galecki, right) and Sheldon (Jim Parsons, left) meet new neighbor Penny, Leonard is excited, but Sheldon is less enthusiastic for he feels his friend is only chasing a dream he'll never catch, on the series premiere of The Big Bang Theory. Photo: Monty Brinton/CBS ©2007 CBS Broadcasting Inc. All Rights Reserved. Flash t-shirt courtesy DC Comics

When Leonard (Johnny Galecki, right) and Sheldon (Jim Parsons, left) meet new neighbor Penny, Leonard is excited, but Sheldon is less enthusiastic for he feels his friend is only chasing a dream he'll never catch, on the series premiere of The Big Bang Theory. Photo: Greg Gayne/Warner Bros. ©2007 Warner Bros. Television. All Rights Reserved. Flash t-shirt courtesy DC Comics

When Leonard (Johnny Galecki, left) and Sheldon (Jim Parsons, right) meet new neighbor Penny, Leonard is excited, but Sheldon is less enthusiastic for he feels his friend is only chasing a dream he'll never catch, on the series premiere of The Big Bang Theory. Photo: Greg Gayne/Warner Bros. ©2007 Warner Bros. Television. All Rights Reserved. Flash t-shirt courtesy DC Comics

When Leonard (Johnny Galecki, left) and Sheldon (Jim Parsons, right) meet new neighbor Penny, Leonard is excited, but Sheldon is less enthusiastic for he feels his friend is only chasing a dream he'll never catch, on the series premiere of The Big Bang Theory. Photo: Greg Gayne/Warner Bros. ©2007 Warner Bros. Television. All Rights Reserved. Flash t-shirt courtesy DC Comics

When Leonard and Sheldon meet new neighbor Penny (Kaley Cuoco, left), Leonard (Johnny Galecki, right) is excited, but Sheldon is less enthusiastic for he feels his friend is only chasing a dream he'll never catch, on the series premiere of The Big Bang Theory. Photo: Greg Gayne/Warner Bros. ©2007 Warner Bros. Television. All Rights Reserved. Flash t-shirt courtesy DC Comics

Brainy best friends Leonard (Johnny Galecki, right) and Sheldon (Jim Parsons, left), can tell you anything you want to know about quantum physics, but when it comes to dealing with everyday life here on earth, they're lost in the cosmos. Neither fully understands that scientific principles don't always apply in matters of the heart - until they meet their sexy new neighbor, Penny (Kaley Cuoco, center), a friendly screenwriter/waitress from the Midwest who also happens to be newly single, on the series premiere of The Big Bang Theory. Photo: Robert Voets/CBS ©2007 CBS Broadcasting Inc. All Rights Reserved.

Brainy best friends Leonard (Johnny Galecki, not pictured) and Sheldon (Jim Parsons, right), can tell you anything you want to know about quantum physics, but when it comes to dealing with everyday life here on earth, they're lost in the cosmos. Neither fully understands that scientific principles don't always apply in matters of the heart - until they meet their sexy new neighbor, Penny (Kaley Cuoco, left), a friendly screenwriter/waitress from the Midwest who also happens to be newly single. Photo: Greg Gayne/Warner Bros. ©2007 Warner Bros. Television. All Rights Reserved. Flash t-shirt courtesy DC Comics

When Leonard and Sheldon meet new neighbor Penny (Kaley Cuoco, pictured), Leonard is excited, but Sheldon is less enthusiastic for he feels his friend is only chasing a dream he'll never catch, on the series premiere of THE BIG BANG THEORY. Photo: Robert Voets/CBS ©2007 CBS Broadcasting Inc. All Rights Reserved.