Checklist: Show More Of You Otezla is a pill that can help you achieve clearer skin.
Posted on Aug 20, 2019 02:40pm

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Prescription medication Otezla is different. It treats moderate to severe plaque psoriasis where it starts—inside the body. Otezla by Celgene is a pill—not a messy cream, and doesn't involve a needle for administration. It is the only treatment of its kind approved to treat plaque psoriasis. People have achieved 75% clearer skin after just 4 months, with reduced redness, thickness, and scaliness of plaques.

Though many people assume that plaque psoriasis is a skin disease, the overactive inflammation associated with it actually starts inside the body. Lab research has shown that an enzyme called phosphodiesterase 4 (PDE4), located inside cells, contributes to this inflammation. Otezla is called a PDE4 inhibitor—meaning it works inside inflammatory cells to reduce PDE4 activity. A reduction in PDE4 activity is thought to help reduce the overactive inflammation that happens in people with plaque psoriasis. Less inflammation can lead to fewer symptoms of plaque psoriasis: that can mean less redness, thickness, and scaliness of plaques.

Talk to your doctor to see if Otezla is right for you. For product information, prescribing information, medication guide, and possible side effects, visit

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